In this work, we report a microfluidic platform that can be easily translated into a biomarker diagnostic. This platform integrates microfluidic technology with electrochemical sensing and embodies a reaction/detection chamber to measure serum levels of different biomarkers. Microfabricated Au electrodes encased in a microfluidic chamber are functionalized to immobilize the antibodies, which can selectively capture the corresponding antigen.

This paper reports a step-wise protocol to immobilize corresponding antibody on gold electrodes for electrochemical measurement of Osteocalcin (Oc), a bone turnover marker, levels in human serum. To our knowledge this is the first such sensor developed for Oc measurement.

Prevalence of osteoporosis is increasing both in developed and developing countries. Due to rapid growth in the burden and cost of osteoporosis, worldwide, it seems reasonable to focus on the reduction of fractures as the main goal of treatment. Although, efficient pharmacological agents are available for the treatment of osteoporosis, there still remains a need to more specific drugs with less adverse effects.

Since 1991 many studies evaluated the link between cardiovascular diseases and osteoporosis, two age-related conditions, but the main common pathologic pathway has not been determined yet. The histological similarity between arterial calcified plaque and bone matrix and involvement of similar cells and mediators provide a special field of research.

Reliable and valid information on burden of road traffic injuries (RTIs) is essential for short-term and long-term planning. We designed the present study to describe the levels and trends of burden of RTIs in Iran from 1990 to 2019.

مطالعه بزرگ و آینده نگر "برنامه سلامت سالمندی بوشهر" با هدف تعیین عوامل مختلف موثر بر سلامت سالمندان و شیوع آنها با هدف فراهم کردن اطلاعات مورد نیاز برای تصمیم گیری پزشکان، سیاست گذاران، مدیران برنامه های بهداشتی و خود سالمندان و برداشتن گام های جدی در جهت پیشگیری از وقوع خطرات ناشی از بروز مشکلات دوران سالمندی و بهبود کیفیت زندگی سالمندان و جلوگیری از تحمیل بار مالی به اقتصاد خانواده ها و جامعه طراحی شده است.

As a surrogate for all relevant risk factors, it is preferable to show trends in the mean cardiovascular disease(CVD) risk rather than to examine each risk factor trend separately.

Decreasing calories, salt, sugar and fat intake is considered the golden solution to reduce obesity and cardiovascular diseases (CVDs) related to unhealthy diet. This study aimed to investigate the health system induced barriers to a healthy diet in Iran.

Stress is known as a conventional risk factor of cardiovascular disease. Nurses work in stressful environment and could be one of the target populations to be assessed for cardio metabolic risk factor.